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It's not just the exploding human appendix. "Intelligent design" is full of idiot engineering when it comes to biology (to say nothing of the broader stage of world-destroying asteroids and supervolcanos and all that).

See an excellent catalog of in excelsis 'Doh!' at Some More of God's Greatest Mistakes. You'll find all your old favorites – Useless cave dweller eyes! Defective human retinas! Male nipples! – along with new reasons to be wonder whether the Seven Days of Creation were in fact a week-long bender.